diff --git a/Installation/cmake/modules/CGAL_ITK_support.cmake b/Installation/cmake/modules/CGAL_ITK_support.cmake
new file mode 100644
index 00000000000..61ed67e2f2b
--- /dev/null
+++ b/Installation/cmake/modules/CGAL_ITK_support.cmake
@@ -0,0 +1,7 @@
+if(ITK_FOUND AND NOT TARGET CGAL::ITK_support)
+  add_library(CGAL::ITK_support INTERFACE IMPORTED)
+  set_target_properties(CGAL::ITK_support PROPERTIES
+    INTERFACE_COMPILE_DEFINITIONS "CGAL_USE_ITK"
+    INTERFACE_INCLUDE_DIRECTORIES "${ITK_INCLUDE_DIRS}"
+    INTERFACE_LINK_LIBRARIES "${ITK_LIBRARIES}")
+endif()
diff --git a/Mesh_3/examples/Mesh_3/CMakeLists.txt b/Mesh_3/examples/Mesh_3/CMakeLists.txt
index aff10c6037b..aa5d716253f 100644
--- a/Mesh_3/examples/Mesh_3/CMakeLists.txt
+++ b/Mesh_3/examples/Mesh_3/CMakeLists.txt
@@ -164,10 +164,10 @@ if(TARGET CGAL::CGAL_ImageIO)
 
     find_package(ITK QUIET COMPONENTS ITKCommon ITKThresholding ITKSmoothing ITKImageIntensity)
     if(ITK_FOUND)
-      include(${ITK_USE_FILE})
+      include(CGAL_ITK_support)
       create_single_source_cgal_program("mesh_3D_weighted_image.cpp")
       target_link_libraries(mesh_3D_weighted_image
-                            PUBLIC CGAL::Eigen3_support ${ITK_LIBRARIES})
+                            PUBLIC CGAL::Eigen3_support CGAL::ITK_support)
     endif(ITK_FOUND)
 
   else()
diff --git a/Polyhedron/demo/Polyhedron/Plugins/Mesh_3/CMakeLists.txt b/Polyhedron/demo/Polyhedron/Plugins/Mesh_3/CMakeLists.txt
index df7f4c7ee35..89d05476c46 100644
--- a/Polyhedron/demo/Polyhedron/Plugins/Mesh_3/CMakeLists.txt
+++ b/Polyhedron/demo/Polyhedron/Plugins/Mesh_3/CMakeLists.txt
@@ -30,9 +30,8 @@ target_include_directories(mesh_3_plugin PRIVATE include)
 
 find_package(ITK QUIET COMPONENTS ITKCommon ITKThresholding ITKSmoothing ITKImageIntensity)
 if(ITK_FOUND)
-  include(${ITK_USE_FILE})
-  target_link_libraries(mesh_3_plugin PUBLIC ${ITK_LIBRARIES})
-  target_compile_definitions(mesh_3_plugin PUBLIC CGAL_USE_ITK)
+  include(CGAL_ITK_support)
+  target_link_libraries(mesh_3_plugin PUBLIC CGAL::ITK_support)
 endif(ITK_FOUND)
 
 find_package(VTK QUIET COMPONENTS vtkImagingGeneral vtkIOImage NO_MODULE)